Inhibition of the Calcium Plateau Following In Vitro Status Epilepticus Prevents the Development of Spontaneous Recurrent Epileptiform Discharges
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چکیده
s/Meetings Nagarkatti, N., Blair, R.E., DeLorenzo, R.J. The role of leaky ryanodine receptors in the rat pilocarpine model of acquired epilepsy. Society for Neurosciences Meeting, Chicago, IL, October 17-21, 2009. Nagarkatti, N., Deshpande, L.S., DeLorenzo, R.J. The prevention of epileptogenesis through calcium modulation in a hippocampal neuronal culture model of status epilepticusinduced acquired epilepsy. Virginia Academy of Sciences, Richmond, VA, May 28-29, 2009. Nagarkatti, N., Deshpande, L.S., DeLorenzo, R.J. The generation and maintenance of a long lasting calcium plateau in cultured hippocampal neurons following in vitro status epilepticus. American Epilepsy Society Meeting, Seattle, WA, Dec. 5-9, 2008. Nagarkatti, N., Deshpande, L.S., Ziobro, J.M., DeLorenzo, R.J. Carisbamate exhibits antiepileptogenic properties mediated through calcium modulation in cultured hippocampal neurons. Society for Neurosciences Meeting, Washington D.C., Nov. 15-19, 2008. Nagarkatti, N., Carter, D.S., Deshpande, L.S., Blair, R.E., DeLorenzo, R.J. The inhibition of the injury-induced calcium plateau through modulation of intracellular calcium stores in an in vitro model of acquired epilepsy. Watts Day Symposium, Richmond, VA, Oct. 30, 2008. Nagarkatti, N. and DeLorenzo, R.J. Levetiracetam inhibits both ryanodine and IP3 mediated calcium induced calcium release in hippocampal neurons in culture. American Epilepsy Society Meeting, Philadelphia, PA, Nov. 30-Dec. 4, 2007. Nagarkatti, N., Deshpande, L.S., Blair, R.E. and DeLorenzo, R.J. The role of the injuryinduced calcium plateau during epileptogenesis in mediating neuronal plasticity changes and the development of acquired epilepsy. Society for Neurosciences Meeting, San Diego, CA, Nov. 3-7, 2007.
منابع مشابه
Progressive, potassium-sensitive epileptiform activity in hippocampal area CA3 of pilocarpine-treated rats with recurrent seizures.
Rat hippocampal area CA3 pyramidal cells synchronously discharge in rhythmic bursts of action potentials after acute disinhibition or convulsant treatment in vitro. These burst discharges resemble epileptiform activity, and are of interest because they may shed light on mechanisms underlying limbic seizures. However, few studies have examined CA3 burst discharges in an animal model of epilepsy,...
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